专业和研究方向:有机合成化学,农药学,化学生物学
研究兴趣及科研方向:以新的有机合成方法学为契机,将新的方法学与农药学、药物化学和化学生物学相结合,开展高效环保的作物保护剂的创制和新的制剂/助剂体系研究。
Ph.D Zhenhua Zhang, Professor The Research in Prof. Zhang’s lab focus on agrochemical discovery and translational research based on new organic synthesis methodologies. Research Experiences: 2018.1-present Professor in Department of Applied Chemistry, China Agriculture University, Beijing 2013.7-2017.12 Associate Professor in Department of Applied Chemistry, China Agriculture University, Beijing 2011.7-2013.6 Fellow / Post doctor of Medicinal Chemistry in Translational Research Center, National Institute of Biological Sciences, Beijing (Advisor: Prof. Zhiyuan Zhang) 2010.4-2011.4 Co-investigator in HIV DPU, Infectious Diseases MDD, GlaxoSmithKline, Research Triangle Park, NC, US 2005.9-2011.7 Ph. D. in Organic Chemistry, Peking University, Beijing (Advisor: Prof. Jianbo Wang) 2001.9-2005.7 B. S. in Applied Chemistry in South China University of Technology, Guangzhou (Advisor: Prof. Huanfeng Jiang) Selected Publications: 1. Zongyang Li, Tongyu Huo, Li Li, Shuo Feng, Qian Wang, Zhen Zhang, Sen Pang, Zhiyuan Zhang, Peng Wang, and Zhenhua Zhang*, Rh-Catalyzed Reaction of Vinyl Azides with Isonitriles and Alkynes/ Benzynes, Org. Lett. 2018, 20, 7762−7766. 2. Yiyang Liu, Zhen Zhang, Songnan Zhang, Yan Zhang, Jianbo Wang*, and Zhenhua Zhang*, Pd0-Catalyzed Four-Component Reaction of Aryl Halide, CO, N-Tosylhydrazone, and Amine, Chem. Asian J. 2018, 13, 3658–3663. (Selected as a VIP paper) 3. Shiyang Xu, Baoliang Huang, Guanyu Qiao, Ziyue Huang, Zhen Zhang, Zongyang Li, Peng Wang, and Zhenhua Zhang*, Rh(III)-Catalyzed C−H Activation of Boronic Acid with Aryl Azide, Org. Lett. 2018, 20, 5578−5582. 4. Yujia Tong, Leihou Shao, Xianlei Li, Jianqing Lu, Huiling Sun, Sheng Xiang, Zhenhua Zhang*, Yan Wu*, and Xuemin Wu*, Adhesive and Stimulus-Responsive Polydopamine-Coated Graphene Oxide System for Pesticide-Loss Control, J. Agric. Food Chem. 2018, 66, 2616−2622. 5. Guanyu Qiao, Zhen Zhang, Baoliang Huang, Liu Zhu, Fan Xiao, and Zhenhua Zhang*, Palladium-Catalyzed One-Pot Synthesis of N-Sulfonyl, N-Phosphoryl, and N-Acyl Guanidines, Synthesis 2018, 50, 330-340. 6. Zhen Zhang, Baoliang Huang, Guanyu Qiao, Liu Zhu, Fan Xiao, Feng Chen, Bin Fu, and Zhenhua Zhang*, Tandem Coupling of Azide with Isonitrile and Boronic Acid: Facile Access to Functionalized Amidines, Angew. Chem. Int. Ed. Engl. 2017, 56, 4320–4323. 7. Jin Zhao, Zongyang Li, Shaole Song, Ming-An Wang, Bin Fu, and Zhenhua Zhang*, Product-Derived Bimetallic Palladium Complex Catalyzes Direct Carbonylation of Sulfonylazides, Angew. Chem. Int. Ed. Engl. 2016, 55, 5545–5549. 8. Jin Zhao, Zongyang Li, Shuaihu Yan, Shiyang Xu, Ming-An Wang, Bin Fu, and Zhenhua Zhang*, Pd/C Catalyzed Carbonylation of Azides in the Presence of Amines. Org. Lett. 2016, 18, 1736−1739. 9. Zhen Zhang, Fan Xiao, Baoliang Huang, Jincheng Hu, Bin Fu, and Zhenhua Zhang*, Cyclization of Alkyne−Azide with Isonitrile/CO via Self-Relay Rhodium Catalysis, Org. Lett. 2016, 18, 908−911. 10. Zhen Zhang, Zongyang Li, Bin Fu and Zhenhua Zhang*, Palladium-catalyzed cross-coupling reaction of azides with isocyanides, Chem. Commun. 2015, 51, 16312-16315. (Selected as Front Cover) 11. Zhenhua Zhang, Yiyang Liu, Lin Ling, Yuxue Li,* Yian Dong, Mingxing Gong, Xiaokun Zhao, Yan Zhang and Jianbo Wang*, Pd-Catalyzed Carbonylation of Diazo Compounds at Atmospheric Pressure: A Catalytic Approach to Ketenes, J. Am. Chem. Soc. 2011, 133, 4330-4341. 12. Zhenhua Zhang, Yan Zhang and Jianbo Wang*, Carbonylation of Metal Carbene with Carbon Monoxide: Generation of Ketene, ACS Catalysis 2011, 1, 1621-1630. 13. Zhenhua Zhang, Yiyang Liu, Mingxing Gong, Yan Zhang and Jianbo Wang*, Palladium-Catalyzed Carbonylation / Acyl Migratory Insertion Cascade, Angew. Chem. Int. Ed. Engl. 2010, 49, 1139-1142. 14. Zhenhua Zhang, Weifeng Shi, Jian Zhang, Bo Zhang, Bingge Liu, Yiyang Liu, Bo Fan, Fengping Xiao, Feng Xu and Jianbo Wang*, Rh(II)-Catalyzed Reaction of a-Diazocarbonyl Compounds Bearing b-Trichloroacetylamino Substituent: C-H Insertion versus 1,2-H Shift, Chem. Asian J. 2010, 5, 1112-1119. 15. Zhenhua Zhang, Jianbo Wang*, Recent Studies on the Reactions of a-Diazocarbonyl Compounds, Tetrahedron, 2008, 64, 6577-6605.
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