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覃兆海
性 别: 学 位: 博士
职 称: 教授 所属系别: 应用化学系
E -- mail : qinzhaohai@263.net
 

 

覃兆海,19641月出生,湖北公安县人,1985年毕业于湖北大学化学系,1992年于中国科学院上海药物研究所获博士学位,1995年入中国农业大学任教,2001年起受聘为教授,博士生导师。长期从事新农药创制合成研究工作,先后发明具有我国自主知识产权的新型杀菌剂丁吡吗啉(Pyrimorph)和新型杀虫剂戊吡虫胍(Guadipyr),并开创一个硝基促进的分子内脱氢芳构化反应。主持和参加了18项国家科研和教改项目,发表论文137篇,其中SCI收录70篇。

 

研究领域:1. 新农药创制;2. 天然产物全合成及结构改造;3. 生物质化学与化工

在研项目:

  1. 选择性ABA类似物的创制及作为脱落酸受体功能化学探针的研究(国家自然科学基金面上项目),项目编号:21572265

2. 杀菌剂丁吡吗啉、候选杀虫剂戊吡虫胍及CAU1204产业化关键技术与应用开发研究(农业部行业专项)项目编号:201203022

3. 科研用有机试剂、特种试剂、有机合成中间体(国家十二五支撑计划项目),项目编号:2015BAK45B01

 

主讲课程:1. 有机化学;2. 现代化学进展;3. 生物质化学与化工;4. 物理有机化学

代表性文章:

 

 1. Yuan, Xiaoyong; Jia, Changqing; Ma, Yongqiang; Yang, Dongyan; Rui, Changhui; Qin, Zhaohai,Synthesis, insecticidal and fungicidal activities of methyl 2-(methoxyimino)-2-(2-((1-(N'-nitrocarbamimidoyl)-2-hydrocarbylidenehydrazinyl)methyl)phenyl)acetatesRSC Advances, 2016, 6(24), 19916-19922,

2. Wang, Mian; Yuan, Yanglei; Wang, Hongmei; Qin, Zhaohai, A fluorescent and colorimetric probe containing oxime-ether for Pb2+ in pure water and living cells, Analyst (Cambridge, United Kingdom), 2016, 141(3), 832-8353. Xiaoqiang Han, Jinlong Fan, Huizhe Lu, Chuan Wan, Xiuyun Li, Hong Li, Dongyan Yang, Yuanzhi Zhang, Yumei Xiao, Zhaohai Qin, Synthesis, resolution and biological evaluation of cyclopropyl analogs of abscisic Acid, Bioorg. Med. Chem., 2015, 23, 6210-62174. Shijie Du, Zaimin Tian, Dongyan Yang, Xiuyun Li, Hong Li, Changqing Jia, Chuanliang Che, Mian Wang and Zhaohai Qin, Synthesis, Antifungal Activity and Structure-Activity Relationships of Novel 3-(Difluoromethyl)-1-methyl-1Hpyrazole-4-carboxylic Acid Amides, Molecules, 2015, 20, 8395-84085. Xiaoqiang Han, Chuan Wan, Xiuyun Li, Hong Li, Dongyan Yang, Shijie Du, Yumei Xiao, Zhaohai Qin, Synthesis and bioactivity of 2,3-benzoabscisic acid analogs, Bioorg. Med. Chem. Lett., 2015, 25(11), 2438-24416. Chuan Wan, Yuanzhi Zhang, Dongyan Yang, Xiaoqiang Han, Xiuyun Li, Hong Li, Yumei Xiao, Zhaohai Qin, Synthesis and biological activity of abscisic acid esters, Phytochem. Lett., 2015, 12, 267-2727. Shijie Du; Huizhe Lu; Dongyan Yang; Hong Li; Xilin Gu; Chuan Wan; Changqing Jia; Mian Wang; Xiuyun Li; Zhaohai Qin, Synthesis, Antifungal Activity and QSAR of Some Novel Carboxylic Acid Amides, Molecules 2015, 20, 4071-40878. Wang, Mian; Liu, Xiaomei; Lu, Huizhe; Wang, Hongmei; Qin, Zhaohai , detected by fluorescence, colorimetry and test paper, ACS Appl. Mater. Interf., 2015, 7(2), 1284-1289A highly selective and reversible chemosensor for Pd2+ 9. Yu-Mei XiaoLothar EsserFei ZhouChang LiYi-Hui ZhouChang-An YuZhao-Hai QinDi Xia, Studies on Inhibition of Respiratory Cytochrome bc1 Complex by the Fungicide Pyrimorph Suggest a Novel Inhibitory Mechanism, Plos One, 2014, 9(4), e9376510. Liu WenjianHan XiaoqiangXiao YumeiFan JinlongZhang YuanzhiLu HuizheWang MinganQin Zhaohai, Synthesis, photostability and bioactivity of 2,3-cyclopropanated abscisic Acid, Phytochem., 2013, 96, 72–8011. Xiaoqiang HanZiyuan ZhouChuan WanYumei XiaoZhaohai Qin, Synthesis of unsaturated carbonyl compounds and aldehydes via a Co(acac)2 catalytic allylic and benzylic oxidation by TBHP, Synthesis, 2013, 45, 0615-062012. Su, Wangcang; Zhou, Yihui; Ma, Yongqiang; Wang, Lei; Zhang, Zheng; Rui, Changhui; Duan, Hongxia; Qin, Zhaohai, N'-Nitro-2-hydrocarbylidenehydrazinecarboximidamides: Design, Synthesis, Crystal Structure, Insecticidal Activity, and Structure-Activity Relationships, J. Agric. Food Chem. , 2012, 60(20), 5028-5034

 

发明专利:

1. 肖玉梅,覃兆海,李红,万川,吴燕华,一种含丁吡吗啉与氟环唑的杀菌组合物,专利号:ZL 2014 1 0151402.1;授权公告日:2015.4.152. 肖玉梅,覃兆海,李红,吴燕华,万川,一种含丁吡吗啉与啶酰菌胺的杀菌组合物,专利号:ZL 2014 1 0151017.7;授权公告日:2015.9.233. 覃兆海,万川,韩小强,陈会春,新型农用杀菌剂丁吡吗啉的合成工艺改进,专利号:ZL 2013 1 0394007.1;授权公告日:2015.12.234.覃兆海,韩小强,万川,肖玉梅,一类高活性苯并异脱落酸类似物及其制备方法,专利号:ZL 2013 1 0388991.0;授权公告日:2013.8.305. 肖玉梅,覃兆海,范锦龙,韩小强,刘文剑,吴燕华,两种种子萌发抑制剂及其应用,ZL 2013 1 0221523.4;授权公告日:2013.6.56. 覃兆海,肖玉梅,刘文剑,范锦龙,韩小强,一种光稳定的顺式2,3-环丙烷化脱落酸类似物及其制备方法,申请号:CN201210391567;申请日:2012.10.16;公开号:CN102911041A;公开日:2013.02.06

 

 


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