专业和研究方向：有机合成化学，农药学，化学生物学

研究兴趣及科研方向：以新的有机合成方法学为契机，将新的方法学与农药学、药物化学和化学生物学相结合，开展高效环保的作物保护剂的创制和新的制剂/助剂体系研究。

Ph.D Zhenhua Zhang, Professor

The Research in Prof. Zhang’s lab focus on agrochemical discovery and translational research based on new organic synthesis methodologies.

Research Experiences:

2018.1-present        Professor in Department of Applied Chemistry, China Agriculture University, Beijing

2013.7-2017.12        Associate Professor in Department of Applied Chemistry, China Agriculture University, Beijing

2011.7-2013.6          Fellow / Post doctor of Medicinal Chemistry in Translational Research Center, National Institute of Biological Sciences, Beijing (Advisor: Prof. Zhiyuan Zhang)

2010.4-2011.4          Co-investigator in HIV DPU, Infectious Diseases MDD, GlaxoSmithKline, Research Triangle Park, NC, US

2005.9-2011.7          Ph. D. in Organic Chemistry, Peking University, Beijing (Advisor: Prof. Jianbo Wang)

2001.9-2005.7          B. S. in Applied Chemistry in South China University of Technology, Guangzhou (Advisor: Prof. Huanfeng Jiang)

Selected Publications:

1. Zongyang Li, Tongyu Huo, Li Li, Shuo Feng, Qian Wang, Zhen Zhang, Sen Pang, Zhiyuan Zhang, Peng Wang, and Zhenhua Zhang*, Rh-Catalyzed Reaction of Vinyl Azides with Isonitriles and Alkynes/ Benzynes, Org. Lett. 2018, 20, 7762−7766.

2. Yiyang Liu, Zhen Zhang, Songnan Zhang, Yan Zhang, Jianbo Wang*, and Zhenhua Zhang*, Pd⁰-Catalyzed Four-Component Reaction of Aryl Halide, CO, N-Tosylhydrazone, and Amine, Chem. Asian J. 2018, 13, 3658–3663. (Selected as a VIP paper)

3. Shiyang Xu, Baoliang Huang, Guanyu Qiao, Ziyue Huang, Zhen Zhang, Zongyang Li, Peng Wang, and Zhenhua Zhang*, Rh(III)-Catalyzed C−H Activation of Boronic Acid with Aryl Azide, Org. Lett. 2018, 20, 5578−5582.

4. Yujia Tong, Leihou Shao, Xianlei Li, Jianqing Lu, Huiling Sun, Sheng Xiang, Zhenhua Zhang*, Yan Wu*, and Xuemin Wu*, Adhesive and Stimulus-Responsive Polydopamine-Coated Graphene Oxide System for Pesticide-Loss Control, J. Agric. Food Chem. 2018, 66, 2616−2622.

5. Guanyu Qiao, Zhen Zhang, Baoliang Huang, Liu Zhu, Fan Xiao, and Zhenhua Zhang*, Palladium-Catalyzed One-Pot Synthesis of N-Sulfonyl, N-Phosphoryl, and N-Acyl Guanidines, Synthesis 2018, 50, 330-340.

6. Zhen Zhang, Baoliang Huang, Guanyu Qiao, Liu Zhu, Fan Xiao, Feng Chen, Bin Fu, and Zhenhua Zhang*, Tandem Coupling of Azide with Isonitrile and Boronic Acid: Facile Access to Functionalized Amidines, Angew. Chem. Int. Ed. Engl. 2017, 56, 4320–4323.

7. Jin Zhao, Zongyang Li, Shaole Song, Ming-An Wang, Bin Fu, and Zhenhua Zhang*, Product-Derived Bimetallic Palladium Complex Catalyzes Direct Carbonylation of Sulfonylazides, Angew. Chem. Int. Ed. Engl. 2016, 55, 5545–5549.

8. Jin Zhao, Zongyang Li, Shuaihu Yan, Shiyang Xu, Ming-An Wang, Bin Fu, and Zhenhua Zhang*, Pd/C Catalyzed Carbonylation of Azides in the Presence of Amines. Org. Lett. 2016, 18, 1736−1739.

9. Zhen Zhang, Fan Xiao, Baoliang Huang, Jincheng Hu, Bin Fu, and Zhenhua Zhang*, Cyclization of Alkyne−Azide with Isonitrile/CO via Self-Relay Rhodium Catalysis, Org. Lett. 2016, 18, 908−911.

10. Zhen Zhang, Zongyang Li, Bin Fu and Zhenhua Zhang*, Palladium-catalyzed cross-coupling reaction of azides with isocyanides, Chem. Commun. 2015, 51, 16312-16315. (Selected as Front Cover)

11. Zhenhua Zhang, Yiyang Liu, Lin Ling, Yuxue Li,* Yian Dong, Mingxing Gong, Xiaokun Zhao, Yan Zhang and Jianbo Wang*, Pd-Catalyzed Carbonylation of Diazo Compounds at Atmospheric Pressure: A Catalytic Approach to Ketenes, J. Am. Chem. Soc. 2011, 133, 4330-4341.

12. Zhenhua Zhang, Yan Zhang and Jianbo Wang*, Carbonylation of Metal Carbene with Carbon Monoxide: Generation of Ketene, ACS Catalysis 2011, 1, 1621-1630.

13. Zhenhua Zhang, Yiyang Liu, Mingxing Gong, Yan Zhang and Jianbo Wang*, Palladium-Catalyzed Carbonylation / Acyl Migratory Insertion Cascade, Angew. Chem. Int. Ed. Engl. 2010, 49, 1139-1142.

14. Zhenhua Zhang, Weifeng Shi, Jian Zhang, Bo Zhang, Bingge Liu, Yiyang Liu, Bo Fan, Fengping Xiao, Feng Xu and Jianbo Wang*, Rh(II)-Catalyzed Reaction of a-Diazocarbonyl Compounds Bearing b-Trichloroacetylamino Substituent: C-H Insertion versus 1,2-H Shift, Chem. Asian J. 2010, 5, 1112-1119.

    15. Zhenhua Zhang, Jianbo Wang*, Recent Studies on the Reactions of a-Diazocarbonyl Compounds, Tetrahedron, 2008, 64, 6577-6605.